Leucovorin Calcium 15 mg Tablets in Pakistan

Leucovorin Calcium 15 mg Tablets in Pakistan

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Leucovorin Calcium 15 mg Tablets in Pakistan Overview

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Leucovorin Calcium 15 Mg Tablets in Pakistan

Leucovorin Calcium 15 Mg Tablets in Pakistan (Calcium Folinate) Is a Active Form of Folic Acid Used as a Rescue Agent to Protect Healthy Cells Following High-Dose Methotrexate Chemotherapy. It Is Also Widely Prescribed to Treat Folate Deficiency, Advanced Megaloblastic Anemia, and to Enhance the Therapeutic Efficacy of 5-Fluorouracil (5-Fu) in Colorectal Cancer Treatment Protocols.

Key Benefits

Methotrexate Toxicity Rescue: Protects Healthy Mucosal and Bone Marrow Cells From the Damaging Effects of High-Dose Methotrexate Therapy.
Enhances Chemotherapy Efficacy: Synergizes With 5-Fluorouracil (5-Fu) to Improve Response Rates in Colorectal Cancer Treatments.
Bypasses Metabolic Blockers: Directly Supplies Active Tetrahydrofolate Without Requiring Activation by the Dihydrofolate Reductase Enzyme.
Treats Severe Folate Deficiency: Rapidly Restores Reduced Folate Pools in Megaloblastic Anemia When Oral Folic Acid Is Ineffective.
Counteracts Antagonist Overdose: Acts as an Antidote for Toxic Overdoses of Folic Acid Antagonists Like Trimethoprim or Pyrimethamine.

How to Use

Administration: Swallow Tablets Whole With a Full Glass of Water. Can Be Taken With or Without Food.
Timing & Rescue Protocol: When Used as Methotrexate Rescue, Timing Is Critical. Take the Exact Prescribed Dose at the Exact Time Intervals Specified by Your Oncologist (Typically Starting 24 Hours After Methotrexate Infusion Begins).
Hydration: Maintain High Daily Fluid Intake During Treatment to Assist Kidney Clearance.
Missed Dose: If Taking This as Part of a Chemotherapy Rescue Schedule and a Dose Is Missed, Contact Your Oncologist Immediately, as Delayed Administration Can Increase Toxic Side Effects.

Key Ingredients

Active Ingredient: Calcium Folinate Equivalent to 15 Mg Leucovorin (Folinic Acid).
Excipients: Microcrystalline Cellulose, Lactose Monohydrate, Starch, Magnesium Stearate, and Colloidal Silicon Dioxide.

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